Characteristically, there is some suppuration at the site of the injury, regional enlargement of the lymph glands and possibly some cellulitis. The full text of this article is available as a pdf 154k. Pasteurella multocidathe major cause of hand infections following domestic animal bites. None of the rapid test systems reliable identified these organisms. Pasteurella sp are distributed worldwide as commensals or parasitic organisms in the upper respiratory and gastrointestinal tracts. Pasteurella multocida is a small nonmotile, nonsporeforming, gramnegative rod or coccobacillus which fails to grow on macconkeys agar. Pasteurella multocida, a gramnegative, facultative, anaerobic coccobacillus, is a common component of the normal oral flora in the majority of cats and dogs, but particularly in cats. More detailed information about the symptoms, causes, and treatments of.
However, the virulence properties of the different subspecies for various hosts have not been elucidated. Pasteurella multocida is a highly versatile pathogen capable of causing infections in a wide range of domestic and wild animals as well as in humans and nonhuman primates. Pasteurella multocida septicemia and subsequent pasteurella dagmatis septicemia in a diabetic patient. Pasteurella multocida is primarily a veterinary pathogen that produces septicemic or respiratory diseases in both domesticated and wild mammals and birds. There are a number of species and sub species, but all are quite similar 2. Multiplex pcr for molecular typing of the capsular antigens of p. Communityacquired pneumonia due to pasteurella multocida mark a marinella md most cases of communityacquired pneumonia result from infection with predictable common pathogens. Here, we characterize the clinical features and outcomes of p multocida infection in a large cohort of patients according to the presence or absence of an animal bite. However, it was not isolated until 1880 by louis pasteur.
Learn vocabulary, terms, and more with flashcards, games, and other study tools. Pasteurella multocida has been shown to produce a toxin that results in necrosis of osteoblasts and stimulation of osteoclastic bone resorption in the nasal. Pasteurellosis in pigs respiratory system veterinary. In recent years, there has been an increase in the incidence of p. Most human pasteurella infections are caused by the multocida species. Pasteurella multocida an overview sciencedirect topics. Your use of this pdf, the bioone complete website, and all posted and associated. Pasteurella sp are small, gramnegative coccobacilli that are pathogens primarily in animals but can cause a variety of infections in humans, usually as a result of a cat or dog bite.
Although skin and soft tissue infections following a cat or dog bite are the more common manifestations of human infection, sporadic cases of pneumonia, lung abscess, and empyema are seen in patients with chronic respiratory diseases. Pasteurella multocida is small gramnegative coccobacillus that is a component of the upper respiratory tract and gastrointestinal flora of many animals. Pasteurella multocida american academy of pediatrics. Pasteurella multocida is a small, gramnegative, facultatively anaerobic coccobacillus that inhabits the normal microbiota of the respiratory tract. Common symptoms of pasteurellosis in humans include swelling, cellulitis, and bloody drainage at the site of the wound. Fatal pasteurella dagmatis peritonitis and septicaemia in. Fowl cholera fc is a highly contagious bacterial disease caused by pasteurella multocida. Molecular characterization of the capsular antigens of pasteurella. It is rarely reported, however, and apparently often overlooked as a pathogen. Pasteurella multocida is part of the normal oral flora of many domestic and wild mammals. However, rare patients develop pneumonia from unusual bacterial species such as. Pasteurella multocida is a rare cause of bacterial meningitis, more frequently affecting humans at the extremes of age. Pasteurella sp are a genus of zoonotic bacteria meaning they can be passed between animals and people.
Strains of the species are currently classified into five serogroups a, b, d, e, f based on capsular composition and 16 somatic serovars 116. Pasteurella multocida urinary tract infection with. Pasteurella multocida is the type species of the genus pasteurella. Clinical features and outcomes of pasteurella multocida. This nonmotile, nonsporeforming, gramnegative coccobacillus is part of normal animal respiratory flora and, therefore, is a common cause of wound infections due to animal bites. Many pasteurella species are opportunistic pathogens that can cause endemic disease and are associated increasingly with epizootic outbreaks. Article information, pdf download for pasteurella multocida. Communityacquired pneumonia due to pasteurella multocida. Corneal ulcer caused by pasteurella multocida american journal. We report a case of pasteurella dagmatis peritonitis and septicaemia in a patient with cirrhosis.
Pdf pasteurella multocida mastitis in cow case report. An infectious disease caused by a bacterium called pasteurella multocida. Porcine dermatitis and nephropathy syndrome pdns is a sporadic, usually fatal disease of growing and finishing pigs that has been recognized in many pigproducing countries. Pasteurella species are part of the normal oral flora of cats. Pasteurella multocida is a gramnegative bacterium responsible for pasteurellosis acute. Manual only the type species of the genus, pasteurella multocida and p.
Fc is seen in both wild and domestic birds, including mammals. Pasteurella multocida is an important cause of subcutaneous infection which often follows bites or scratches from cats and dogs. Click on the buttons on the tree to retrace your steps or to repeat a segment. The disease most frequently presents in birds as an acute septicaemia, where death may be the first sign observed. Dog and domestic cat bites are major public health problems, and guidelines for their management have been established as a result of careful microbiological 46 and clinical studies. Human infections are most commonly caused by cat and dog bites. Pasteurella multocida, a zoonotic infectious organism, has most often been described in patients after an animal bite. Typing of pasteurella multocida isolated from pigs with. An unusual case of pasteurella multocida bacteremic meningitis. Pasteurella multocida is a gramnegative nonmotile coccobacillus that causes pasteurellosis, also known as snuffles, the primary respiratory disease affecting domestic rabbits deeb and digiacomo, 2000. Pasteurella multocida infections in rabbits may remain subclinical or can cause a variety of acute or chronic diseases in most organs, particularly tissue in the repiratory and genital tracts.
Pasteurella multocida isolates involved in these outbreaks. It is often transmitted through bites and scratches from pets and it can be found in mammals and fowl. Pasteurellosis is most commonly seen in pigs as a complication of mycoplasmal pneumonia see mycoplasmal pneumonia, although swine influenza, aujeszky disease, bordetella bronchiseptica, or haemophilus parahaemolyticus may also cause changes in the lungs that lead to disease caused by pasteurella spp. Pasteurella multocida strains isolated from 15 pigs with pdns and 51 pigs without. Pasteurella multocida is a gramnegative, nonmotile coccobacillus that is penicillinsensitive. Serious pasteurella multocida infections from lion and. Genetic and phylogenetic characteristics of pasteurella. Zoonotic transmission to humans usually occurs through animal bites or contact with nasal secretions, with p. We propose that his bacteraemia might have resulted from direct inoculation of p multocida via his cat licking the venous stasis ulcers on his legs. In humans, rapidly developing pasteurella multocida cellulitis after a cat scratch or bite is a well. Pdf pasteurella multocida and bovine respiratory disease. Of the pasteurella sp known to infect humans, p multocida is the most important. Systemic infections are less common and are limited to patients at the extremes of age or those who have serious underlying disorders, including cirrhosis. Pasteurella multocida symptoms, diagnosis, treatments and.
The most common manifestation in children is cellulitis at the site of a bite or scratch of a cat, dog, or other animal. The organism can occur as a commensal in the nasopharyngeal region of apparently healthy animals. Pasteurella multocida infections american academy of. We present a case of fulminant pasteurella multocida sepsis in a 66yearold man who had undergone a renal transplant. Pasteurella multocida is a gramnegative, nonmotile, penicillinsensitive coccobacillus of the family pasteurellaceae. Septic shock due to pasteurella multocida bacteremia. Identification of pasteurella multocida and pasteurella. Pasteurella multocida is a pathogenic gramnegative bacterium that has been classified into three subspecies, five capsular serogroups and 16 serotypes. Pasteurella multocida is a highly diverse group of bacteria. Pasteurella multocida is known to form part of the normal flora in the nasopharynx or gastrointestinal tract in many domestic and wild animals. Pasteurella multocida is a common cause of infection following bites or scratches caused by dogs and especially cats.
Pasteurella multocida is a leading cause of respiratory diseases in many host species. Pasteurella multocida and mannheimia haemolytica isolates 751 and 514 strains, respectively were highly. Pasteurella haemolytica is a species that infects mainly cattle and horses. Pasteurella multocidathe major cause of hand infections. Despite over 5 years of research, the molecular basis for the myriad manifestations of p. Our patient lived with two dogs and a cat with which he was very close. The species pasteurella multocida includes a heterogeneous group of gramnegative bacteria that are inhabitants of the upper respiratory tract of many vertebrate hosts, including birds, cattle, swine, cats, dogs and rodents. Pasteurella multocida subspecies multocida is the most common cause of fowl cholera, although p. Since that time, pasteurella multocida has been recognize. Petrelated pasteurella multocida induced peritonitis in. Pasteurella multocida simple english wikipedia, the free. Icahn school of medicine at mount sinai, new york, ny open the mouth of most dogs or cats and you will likely find the bacterium pasteurella multocida. Shanson mb, frcpath, in microbiology in clinical practice second edition, 1989. The organism is stained evenly with aniline dyes in a smear from an.
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